A review published this month 'The Immune System in Pediatric Seizures and Epilepsies' aims to present current knowledge of the role of immunity in relation to seizures, with a particular emphasis on clinical data available in childhood. More specifically, various autoantibodies involved in autoimmune encephalitis and epilepsy and general pathophysiological hypotheses on the role of immunity in seizure genesis are discussed, specific epilepsy syndromes in which autoimmune components have been studied are summarized, workup recommendations and therapeutic options are suggested, and finally, open questions and future needs are presented. The full text of this article is available to you via your NHS OpenAthens login (if you don't have an login register here for free).
Things about NEC...
A recent article 'Reducing Incidence of Necrotizing Enterocolitis' reports the following key points.
- Own mother’s milk (OMM) is associated with reduced odds of necrotizing enterocolitis (NEC) in observational studies, and quality improvement (QI) efforts to increase OMM have been successful at decreasing NEC.
- Donor milk (DM) has also been associated with NEC reduction when OMM is unavailable, although DM has not been associated with other health benefits as seen with OMM feedings in preterm infants.
- Institution of standardized feeding guidelines has been associated with reduced NEC rates, although the optimal rates of advancement and fortification are uncertain. Prolonged periods of nothing by mouth are associated with increased rates and severity of NEC and thus enteral feedings should be instituted soon after birth.
- Acid antagonists and prolonged empiric antibiotics in the setting of negative cultures are associated with increased odds of NEC, and both should be minimized or avoided if possible.
- Probiotics have been associated with reduced NEC in some, but not all, studies. Meta-analyses demonstrate reduction in NEC. At present, however, there remains controversy about probiotics due to concerns regarding quality and reliability of available products.
- Anemia and blood transfusions have been linked to NEC. Controversy remains regarding these relationships and best practices regarding enteral feeding during blood transfusions.
Things about dairy intake and blood pressure...
An article published in Journal of American Heart Association has looked at the relationship between dairy intake and blood pressure in black and white children and adolescents enrolled in a weight management program.
What Is New?
- We observed racial differences for the effects of dairy intake on systolic blood pressure (BP) in a cohort of children and teens enrolled in a weight management program.
- Greater intakes of dairy were associated with lower systolic BP in white but not black children and teens, suggesting that greater dairy intake alone is not beneficial for all races regarding systolic BP.
What Are the Clinical Implications?
- Nutrition professionals should assess the quality of the overall dietary pattern, as opposed to single nutrients, when providing recommendations to lower BP in the overweight and obese childhood and adolescent population.
- Nutrition and medical professionals must consider non-nutrition factors contributing to childhood hypertension and other cardiovascular disease risk factors, as current dietary recommendations appear to have differential outcomes across races in this cohort of children and teens.
- To prevent or manage high BP in children and teens, nutrition and medical professionals should use a strong evidence base and work collaboratively to design patient‐focused nutrition interventions taking into account age, sex, and race.
Things coming soon...
Going Public: International Art Collectors in Sheffield continues at the Graves Gallery this autumn with one of the UK’s finest private collections of modern and contemporary art.
Bridget Riley, Red Overture, 2012 © Bridget Riley, 2017 |
This new exhibition showcases personally selected highlights from the collection, including painting, sculpture, works on paper and photography by Carl Andre, Donald Judd, Josef Albers, Anni Albers, Bridget Riley, Lewis Baltz and more.
Saturday 2 September 2017 - Saturday 2 December 2017
Things about health outcomes...
The Local Government Association has published a report 'Partnership approaches to improving health outcomes for young people' - the case studies in this report showcase different approaches to supporting the health of young people. Whilst the approach and focus of the work in local areas varies, each case study provides an opportunity to reflect on what made the initiative a success and how we might use this learning in our own areas.
Things to bake...
One of my favourite food bloggers is Clotildel and her blog is called 'Chocolate & Zucchini' it occurs to me that any gardeners out there may be looking at a glut of courgettes (zucchini) at the moment and need inspiration on how to use them...so here is a cake to come to your rescue 'Chocolate and zucchini cake'
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